We are delighted to announce that our course series entitled “Human Brain Mapping” organized through the Human Brain Mapping Laboratory at the University of Pittsburgh Medical Center will take place as planned this academic year Jul 21 - Jun 22. The course has been held at UPMC since 2019, and at Yale 2013-2018 and had attracted local students, international scholars, neurology/neurosurgery faculty and post-doc in multiple subdomains. This course is open to everyone, is not credited, and does not require registration.

Course Coordinator:

Rafeed Alkawadri, MD

Purpose:

In the last few decades there has been an enormous growth in neuroimaging and electrophysiology techniques for human brain mapping ranging from high resolution and frequency digitized EEG , electrical stimulation, neuromodulation, volumetric and functional MRI to many other modalities such as MR Spectroscopy, PET and EEG.

The University of Pittsburgh Medical Center has world-class electrophysiology and neuroimaging infrastructure and facilities and leaders in many of these fields. The goal of this course is to make these outstanding resources available and encourage their use in clinical neuroscience disease-oriented research. The series will emphasize training on electrophysiology neuroimaging fundamentals, applications of specific techniques to relevant disorders of the nervous system. The lectures will take place on Fridays, and are held biweekly.

Location: 3471 Fifth avenue | LKB 8th floor - Suite 815 | Pittbsurgh, PA 15213 | Time: 12-1pm

The Human Brain Mapping Program at the University of Pittsburgh Comprehensive Epilepsy Center offers a 1- year fellowship that involves i. Course on theoretical aspects of electrical cortical stimulation and electrocorticography ii. Workshops on EEG and image processing iii. Clinical Observership in mapping and intracranial EEG iv. Mentoring in research and manuscript writing

SCHEDULE
Course details (held biweekly)
Functional Mapping by Electrical Cortical Stimulation (ECS)
1. Brief history of electrical cortical stimulation
2. Stimulation and measurements
3. Temporal summation and refractory periods
4. Overview of language mapping
5. Motor and sensory mapping
6. After-discharges
7. ECS induced seizures
8. Mapping in Children: Methodological considerations
9. Intraoperative language mapping
10. Special cases
11. Cingulate/insular/parietal/temporal mapping by ECS
12. Cognitive mapping by ECS
13. Other uses of electrical cortical stimulation

Basics of Clinical Electrocorticography ECoG
1. Overview of electrocorticography
2. Intraoperative electrocorticography and anesthetic considerations
3. Review of evoked potentials

Workshop on EEG and ECoG signal processing
1. Basics of signal processing and filters
2. Practical sessions: ABCs of high frequency oscillations
3. Practical sessions: ABCs of cortico-cortical evoked potentials CCEPs and averaging
4. Practical session: ABCs of gamma mapping
5. Source localization techniques for intracranial EEG

Workshop on image processing
1. MRI basics
2. MRI data analysis steps
3. Functional connectivity basics
4. MRI practical session