Authors: Alkawadri R, Burgess RC, Kakisaka Y, Mosher JC, Alexopoulos AV.

To read the full article please visit JAMA Neurology website

Key Points

Question  What is the chance of recording a seizure and the localizing yield of seizures recorded during routine magnetoencephalography (MEG) studies?

Findings  In this medical record analysis of 44 patients, MEG provided unique and more focal localization information, including in some electroencephalography and interictal MEG silent cases and in some cases that were nonlocalizable otherwise. Extended-source localization was more suitable for analysis of ictal rhythms than commonly used single-point solutions.

Meaning  If feasible, ictal MEG should be sought and considered in presurgical evaluation of drug-resistant epilepsy.